Fc epsilon RI/FCER1A Protein (AA 26-204) (Fc Tag)
Quick Overview for Fc epsilon RI/FCER1A Protein (AA 26-204) (Fc Tag) (ABIN6952258)
Target
See all Fc epsilon RI/FCER1A (FCER1A) ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 26-204
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Purification tag / Conjugate
- This Fc epsilon RI/FCER1A protein is labelled with Fc Tag.
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Fc Fragment of IgE Receptor Ia (FCER1A) (AA 26-205) (Active) protein (hFc Tag)
FCER1A Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC Active
Fc Fragment of IgE Receptor Ia (FCER1A) (AA 26-205) (Active) protein (His tag)FCER1A Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Fc Fragment of IgE Receptor Ia (FCER1A) (AA 24-204) (Active) protein (hFc Tag)FCER1A Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Fc Fragment of IgE Receptor Ia (FCER1A) (AA 1-257) protein (GST tag)FCER1A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Fc Fragment of IgE Receptor Ia (FCER1A) (AA 26-205) protein (His tag)FCER1A Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Fc Fragment of IgE Receptor Ia (FCER1A) protein (Fc Tag)FCER1A Origin: Mouse Host: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
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Storage
- -20 °C
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- Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
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Alternative Name
- Fc epsilon RI alpha
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Background
- High affinity immunoglobulin epsilon receptor subunit alpha (FCER1A) is also known as Fc-epsilon RI-alpha (FcERI), IgE Fc receptor subunit alpha, FCE1A. FCER1A contains two Ig-like (immunoglobulin-like) domains. FCER1A binds to the Fc region of immunoglobulins epsilon and is a high affinity receptor. FCER1A is responsible for initiating the allergic response, which binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines. FCER1A plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma.
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Molecular Weight
- 47.3 kDa
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NCBI Accession
- NP_001992
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Pathways
- Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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