IL17C Protein (AA 19-197) (His tag)
Quick Overview for IL17C Protein (AA 19-197) (His tag) (ABIN6952297)
Target
See all IL17C ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 19-197
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Purification tag / Conjugate
- This IL17C protein is labelled with His tag.
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Interleukin 17C (IL17C) (AA 19-197) (Active) protein (His-Avi Tag)
IL17C Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE Active
Interleukin 17C (IL17C) (AA 1-197) protein (GST tag)IL17C Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 17C (IL17C) (AA 19-197) protein (Fc Tag)IL17C Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Interleukin 17C (IL17C) (AA 19-197) (Active) protein (His tag,AVI tag,Biotin)IL17C Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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- IL17C (Interleukin 17C (IL17C))
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Alternative Name
- IL-17C
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Background
- Interleukin-17C(IL-17C) is a glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. IL-17C binds to IL-17 RE with high affinity and to IL-17 RA with low affinity, binds to a heterodimer formed by IL17RA and IL17RE. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes.
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Molecular Weight
- 21.6 kDa
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NCBI Accession
- NP_037410
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Pathways
- Cellular Response to Molecule of Bacterial Origin
Target
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