TNFSF8 Protein (mFc-His Tag)
Quick Overview for TNFSF8 Protein (mFc-His Tag) (ABIN6961111)
Target
See all TNFSF8 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This TNFSF8 protein is labelled with mFc-His Tag.
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Purpose
- Recombinant human CD30 Ligand Protein with N-terminal mouse Fc and C-terminal 6xHis tag
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Specificity
- MFc (Pro99-Lys330) CD30 Ligand (Gln63-Asp234) 6xHis
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Characteristics
- Extracellular Domain Protein
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 63-234) protein (mFc Tag)
TNFSF8 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC,
Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 63-234) protein (His tag)TNFSF8 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 1-239) protein (His tag)custom-made TNFSF8 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 1-234) protein (His tag)custom-made TNFSF8 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 63-234) protein (His-DYKDDDDK-Strep II Tag)TNFSF8 Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 63-234) (Active) protein (His tag)TNFSF8 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 1-234) protein (GST tag)TNFSF8 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 63-234) protein (His tag)TNFSF8 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 85 % by SDS - PAGE SDS
Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) proteinTNFSF8 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 63-234) (Active) protein (Fc Tag)TNFSF8 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- TNFSF8 (Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8))
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Alternative Name
- CD30 Ligand
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Background
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30 lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- predicted molecular mass of 48.0 kDa after removal of the signal peptide.The apparent molecular mass of mFc-CD30 Ligand-His is 53-70 kDa due to glycosylation.
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Gene ID
- 944
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UniProt
- P32971
Target
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