TNFRSF12A Protein (AA 28-80) (mFc Tag)
Quick Overview for TNFRSF12A Protein (AA 28-80) (mFc Tag) (ABIN6961150)
Target
See all TNFRSF12A ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 28-80
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Purification tag / Conjugate
- This TNFRSF12A protein is labelled with mFc Tag.
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Purpose
- Recombinant human TweakR protein with C-terminal mouse Fc tag
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Specificity
- TweakR(Glu28-Pro80) mFc(Pro99-Lys330)
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Characteristics
- Extracellular Domain Protein
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) (Active) protein
TNFRSF12A Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) (AA 28-80) (Active) protein (hFc Tag)TNFRSF12A Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) (AA 28-129) protein (GST tag)TNFRSF12A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) (AA 28-78) protein (Fc Tag)TNFRSF12A Origin: Mouse Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM
Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) (AA 28-80) (Active) protein (hFc Tag)TNFRSF12A Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) (AA 28-80) protein (His-IF2DI Tag)TNFRSF12A Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) (AA 28-80) protein (hIgG-His-tag)TNFRSF12A Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % SDS
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Application Notes
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
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Comment
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The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please see Certificate of Analysis for specific instructions of reconstitution.
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- TNFRSF12A (Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))
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Alternative Name
- TweakR
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Background
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TNFRSF12A,FGF-inducible 14,FN14,TweakR,CD266
TNFRSF12A (TNF Receptor Superfamily Member 12A) is a Protein Coding gene. Diseases associated with TNFRSF12A include Multiple Sclerosis and Stroke,Ischemic. Among its related pathways are ERK Signaling and CDK-mediated phosphorylation and removal of Cdc6 -
Molecular Weight
- predicted molecular mass of 31.8 kDa after removal of the signal peptide.
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Gene ID
- 51330
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UniProt
- Q9NP84
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Pathways
- Apoptosis, Regulation of Cell Size
Target
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