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CD70 Protein (AA 39-193) (His tag,Fc Tag)

Recombinant CD70 protein expressed in HEK-293 Cells.

SDS

ELISA

2 images

Catalog No. ABIN6961169

$800.30

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Shipping to: United States

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Quick Overview for CD70 Protein (AA 39-193) (His tag,Fc Tag) (ABIN6961169)

Target

See all CD70 Proteins

CD70 (CD70 Molecule (CD70))

Protein Type

Recombinant

Origin

Human

Source

HEK-293 Cells

Application

Screening Assay (ScA), Immunoassay (IA), Antibody Drug Assay (ADA), Affinity Measurement (AM)

Purity

The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Discover our top product CD70 Protein

Protein Characteristics

AA 39-193

Purification tag / Conjugate

This CD70 protein is labelled with His tag,Fc Tag.

Purpose

Recombinant human CD70 protein with C-terminal human Fc and 6xHis tag

Specificity

CD70(Gln39-Pro193) hFc(Glu99-Ala330) 6xHis

Characteristics

Extracellular Domain Protein

Purification

Purified from cell culture supernatant by affinity chromatography
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Product

Expression System

Conjugate

Origin

Price starts at

CD70 Protein (AA 1-193) (His tag)

Expression System HEK-293 Cells

Conjugate His tag

Origin Human

Price starts at $16,231.82

CD70 Protein (AA 1-193) (Strep Tag)

Expression System Cell-free protein synthesis (CFPS)

Conjugate Strep Tag

Origin Human

Price starts at $20,480.57

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CD70 Molecule (CD70) (AA 39-193) (Active) protein (hFc Tag)
CD70 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active

CD70 Molecule (CD70) (AA 99-330) protein (His tag,mFc Tag)
CD70 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM

CD70 Molecule (CD70) (AA 45-195) (Active) protein (hFc Tag)
CD70 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active

CD70 Molecule (CD70) (AA 50-193), (Trimer) (Active) protein (His tag)
CD70 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active

CD70 Molecule (CD70) (AA 50-193), (Trimer) (Active) protein (Biotin,His tag)
CD70 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active

CD70 Molecule (CD70) (AA 1-195) protein (His tag)
custom-made CD70 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

CD70 Molecule (CD70) (AA 1-193) protein (His tag)
custom-made CD70 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

CD70 Molecule (CD70) (AA 39-194) (Active) protein (His tag)
CD70 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active

CD70 Molecule (CD70) (AA 52-193) protein (His-DYKDDDDK-Strep II Tag)
CD70 Origin: Human Host: HEK-293T Cells Recombinant WB, SDS, ELISA, PI

CD70 Molecule (CD70) (AA 52-193) (Active) protein (DYKDDDDK Tag,His tag)
CD70 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active

Application Notes
Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
Comment

The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage

-20 °C,-80 °C

Storage Comment

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date

12 months
Target

CD70 (CD70 Molecule (CD70))

Alternative Name

CD70

Background

CD70,CD27LG,TNFSF7,TNFSF7G,CD27L
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

Molecular Weight

predicted molecular mass of 44.1 kDa after removal of the signal peptide.

Gene ID

970

UniProt

P32970

Pathways

Cancer Immune Checkpoints