TACSTD2 Protein (AA 27-274) (His tag,mFc Tag)

Catalog No. ABIN6961178

Recombinant TACSTD2 protein expressed in HEK-293 Cells.

Quick Overview for TACSTD2 Protein (AA 27-274) (His tag,mFc Tag) (ABIN6961178)

Target: TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA), Screening Assay (ScA)

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Product Details

Protein Characteristics: AA 27-274

Purification tag / Conjugate: This TACSTD2 protein is labelled with His tag,mFc Tag.

Purpose: Recombinant human Trop2 protein with C-terminal mouse Fc and 6xHis tag

Specificity: Trop2(His27-Thr274) mFc(Pro99-Lys330) 6xHis tag

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Application Details

Application Notes: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Comment:

The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Alternative Name: Trop2

Background: TACSTD2,GA733-1,M1S1,TROP2
This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.

Molecular Weight: predicted molecular mass of 54.9 kDa after removal of the signal peptide.The apparent molecular mass of Trop2-mFc-His is 55-70 kDa due to glycosylation.

Gene ID: 4070

UniProt: P09758