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CD80 Protein (CD80) (AA 35-242) (mFc-His Tag)

Recombinant CD80 protein expressed in HEK-293 Cells.
Catalog No. ABIN6964082

Quick Overview for CD80 Protein (CD80) (AA 35-242) (mFc-His Tag) (ABIN6964082)

Target

See all CD80 Proteins
CD80

Protein Type

Recombinant

Origin

  • 28
  • 18
  • 5
  • 5
  • 3
  • 3
Human

Source

  • 27
  • 7
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
HEK-293 Cells

Purity

The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
  • Protein Characteristics

    AA 35-242

    Purification tag / Conjugate

    This CD80 protein is labelled with mFc-His Tag.

    Purpose

    Recombinant Human B7-1 Protein with C-terminal Mouse Fc and 6xHis tag

    Specificity

    B7-1 (Val35-Asn242) mFc (Pro99-Lys330) 6xHis tag

    Characteristics

    Extracellular Domain Protein

    Purification

    Purified from cell culture supernatant by affinity chromatography
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Expiry Date

    12 months
  • Target

    CD80

    Alternative Name

    B7-1

    Background

    The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.

    Molecular Weight

    predicted molecular mass of 50.9 kDa after removal of the signal peptide. The apparent molecular mass of B7-1-mFc-His is 70-130 kDa due to glycosylation.

    Gene ID

    941

    UniProt

    P33681

    Pathways

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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