CD80 Protein (CD80) (AA 35-242) (mFc-His Tag)
Quick Overview for CD80 Protein (CD80) (AA 35-242) (mFc-His Tag) (ABIN6964082)
Target
See all CD80 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 35-242
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Purification tag / Conjugate
- This CD80 protein is labelled with mFc-His Tag.
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Purpose
- Recombinant Human B7-1 Protein with C-terminal Mouse Fc and 6xHis tag
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Specificity
- B7-1 (Val35-Asn242) mFc (Pro99-Lys330) 6xHis tag
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Characteristics
- Extracellular Domain Protein
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- CD80
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Alternative Name
- B7-1
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Background
- The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.
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Molecular Weight
- predicted molecular mass of 50.9 kDa after removal of the signal peptide. The apparent molecular mass of B7-1-mFc-His is 70-130 kDa due to glycosylation.
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Gene ID
- 941
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UniProt
- P33681
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Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Target
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