CXCR5 Protein (AA 1-53) (Fc Tag)

Catalog No. ABIN6964155

This Recombinant CXCR5 protein is produced in HEK-293 Cells.

Quick Overview for CXCR5 Protein (AA 1-53) (Fc Tag) (ABIN6964155)

Target: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA), Screening Assay (ScA)

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Product Details

Protein Characteristics: AA 1-53

Purification tag / Conjugate: This CXCR5 protein is labelled with Fc Tag.

Purpose: Recombinant Human CXCR5 with C-terminal human Fc tag

Specificity: CXCR5(Met1-Phe53) hFc(Glu99-Ala330)

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Application Details

Application Notes: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Comment:

The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Alternative Name: CXCR5

Background: Blr1,CXC-R5,CXCR-5,Gpcr6,MDR15
Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes.[UniProtKB/Swiss-Prot Function]

Molecular Weight: predicted molecular mass of 32.3 kDa after removal of the signal peptide. The apparent molecular mass of CXCR5-hFc is 35-55 kDa due to glycosylation.

UniProt: P32302