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CD4 Protein (CD4) (Fc Tag)

This Recombinant CD4 protein is expressed in HEK-293 Cells.
Catalog No. ABIN6964180

Quick Overview for CD4 Protein (CD4) (Fc Tag) (ABIN6964180)

Target

See all CD4 Proteins
CD4

Protein Type

Recombinant

Origin

  • 32
  • 8
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Source

  • 30
  • 8
  • 8
  • 2
  • 1
  • 1
  • 1
  • 1
HEK-293 Cells
  • Purification tag / Conjugate

    This CD4 protein is labelled with Fc Tag.

    Sequence

    CD4(Lys26-Trp390)+hFc(Glu99-Ala330)

    Characteristics

    Tagged Protein: C-Human Fc tag

    Purification

    affinity purification
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  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Reconstitute with deionized water

    Buffer

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    Preservative

    Without preservative

    Storage

    -80 °C

    Storage Comment

    Store at -80°C for 12 months (Avoid repeated freezing and thawing)

    Expiry Date

    12 months
  • Target

    CD4

    Alternative Name

    CD4

    Background

    Synonymes: CD4,CD4mut,LEU3
    Description: This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

    Molecular Weight

    65.67 kDa

    UniProt

    P01730

    Pathways

    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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