DPP4 Protein (Fc Tag)
Quick Overview for DPP4 Protein (Fc Tag) (ABIN6964218)
Target
See all DPP4 ProteinsProtein Type
Origin
Source
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Purification tag / Conjugate
- This DPP4 protein is labelled with Fc Tag.
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Sequence
- ADABP(Asn29-Pro766)+hFc(Glu99-Ala330)
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Characteristics
- Tagged Protein: C-Human Fc tag
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Purification
- affinity purification
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute with deionized water
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Preservative
- Without preservative
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Storage
- -80 °C
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Storage Comment
- Store at -80°C for 12 months (Avoid repeated freezing and thawing)
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Expiry Date
- 12 months
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- DPP4 (Dipeptidyl-Peptidase 4 (DPP4))
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Alternative Name
- ADABP
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Background
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Synonymes: ADABP, ADCP2, CD26, DPPIV, TP103
Description: The DPP4 gene encodes dipeptidyl peptidase 4, which is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic type II transmembrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. Dipeptidyl peptidase 4 is highly involved in glucose and insulin metabolism, as well as in immune regulation. This protein was shown to be a functional receptor for Middle East respiratory syndrome coronavirus (MERS-CoV), and protein modeling suggests that it may play a similar role with SARS-CoV-2, the virus responsible for COVID-19. [provided by RefSeq, Apr 2020] -
Molecular Weight
- 116.71 kDa
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UniProt
- P27487
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Pathways
- Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity
Target
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