Adenosine A3 Receptor Protein (ADORA3) (Fc Tag)

Catalog No. ABIN6964222

This Recombinant Adenosine A3 Receptor protein is expressed in HEK-293 Cells.

Quick Overview for Adenosine A3 Receptor Protein (ADORA3) (Fc Tag) (ABIN6964222)

Target: Adenosine A3 Receptor (ADORA3)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Product Details

Purification tag / Conjugate: This Adenosine A3 Receptor protein is labelled with Fc Tag.

Sequence: ADORA3(Trp149-Met177)+hFc(Glu99-Ala330)

Characteristics: Tagged Protein: C-Human Fc tag

Purification: affinity purification

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Preservative: Without preservative

Storage: -80 °C

Storage Comment: Store at -80°C for 12 months (Avoid repeated freezing and thawing)

Expiry Date: 12 months

Target Details

Target: Adenosine A3 Receptor (ADORA3)

Alternative Name: ADORA3

Background: Synonymes: A3AR
Description: This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Alternative splicing results in multiple transcript variants. This gene shares its 5' terminal exon with some transcripts from overlapping GeneID:57413, which encodes an immunoglobulin domain-containing protein. [provided by RefSeq, Nov 2014]

Molecular Weight: 38.72 kDa

UniProt: P0DMS8

Pathways: Hormone Transport, cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process