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ERG Protein (Fc Tag)

ERG Origin: Human Host: HEK-293 Cells Recombinant
Catalog No. ABIN6964259
  • Target See all ERG Proteins
    ERG (ERG, ETS transcription factor (ERG))
    Protein Type
    Recombinant
    Origin
    • 10
    • 2
    • 1
    • 1
    Human
    Source
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This ERG protein is labelled with Fc Tag.
    Sequence
    ERG(Val280-Glu405)+hFc(Glu99-Ala330)
    Characteristics
    Tagged Protein: C-Human Fc tag
    Purification
    affinity purification
    Top Product
    Discover our top product ERG Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Preservative
    Without preservative
    Storage
    -80 °C
    Storage Comment
    Store at -80°C for 12 months (Avoid repeated freezing and thawing)
    Expiry Date
    12 months
  • Target
    ERG (ERG, ETS transcription factor (ERG))
    Alternative Name
    ERG (ERG Products)
    Synonyms
    erg-3 Protein, p55 Protein, erg Protein, erg_A Protein, zgc:103429 Protein, erg_E Protein, ERG Protein, D030036I24Rik Protein, KCNH2 Protein, ERG, ETS transcription factor Protein, v-ets avian erythroblastosis virus E26 oncogene homolog L homeolog Protein, v-ets avian erythroblastosis virus E26 oncogene homolog Protein, v-ets avian erythroblastosis virus E26 oncogene homolog S homeolog Protein, ETS transcription factor Protein, potassium voltage-gated channel subfamily H member 6 Protein, ERG Protein, Erg Protein, erg.L Protein, erg Protein, erg.S Protein, KCNH6 Protein
    Background
    Synonymes: erg-3, p55
    Description: This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. More than two dozens of transcript variants generated from combinatorial usage of three alternative promoters and multiple alternative splicing events have been reported, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Apr 2014]
    Molecular Weight
    49.39 kDa
    UniProt
    P11308
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