RHOC Protein (AA 1-190) (Fc Tag)
Quick Overview for RHOC Protein (AA 1-190) (Fc Tag) (ABIN6964315)
Target
See all RHOC ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 1-190
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Purification tag / Conjugate
- This RHOC protein is labelled with Fc Tag.
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Purpose
- Recombinant Human RHOC Protein with C-terminal human Fc tag
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Specificity
- RHOC (Met1-Cys190) hFc (Glu99-Ala330)
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Characteristics
- Extracellular Domain Protein
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- RHOC (Ras Homolog Gene Family, Member C (RHOC))
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Alternative Name
- RhoC
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Background
- This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
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Molecular Weight
- predicted molecular mass of 47.8 kDa after removal of the signal peptide. The apparent molecular mass of RHOC-hFc is 35-55 kDa due to glycosylation.
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UniProt
- P08134
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Pathways
- WNT Signaling, Cell-Cell Junction Organization
Target
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