TM4SF1 Protein (AA 99-330) (Fc Tag)

Catalog No. ABIN6964380

This Recombinant TM4SF1 protein is produced in HEK-293 Cells.

Quick Overview for TM4SF1 Protein (AA 99-330) (Fc Tag) (ABIN6964380)

Target: TM4SF1 (Transmembrane 4 L Six Family Member 1 (TM4SF1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA), Screening Assay (ScA)

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Product Details

Protein Characteristics: AA 99-330

Purification tag / Conjugate: This TM4SF1 protein is labelled with Fc Tag.

Purpose: Recombinant human TM4SF1 protein with N-terminal Human Fc tag

Specificity: HFc(Glu99-Ala330) TM4SF1 (Pro31-Phe49)

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Application Details

Application Notes: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Comment:

The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: TM4SF1 (Transmembrane 4 L Six Family Member 1 (TM4SF1))

Alternative Name: TM4SF1

Background: H-L6,L6,M3S1,TAAL6
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas.

Molecular Weight: predicted molecular mass of 28.4 kDa after removal of the signal peptide.

Gene ID: 4071

UniProt: P30408