SARS-CoV-2 Spike S2 Protein (SARS-CoV-2 S2) (P.1 - gamma) (His tag)
Quick Overview for SARS-CoV-2 Spike S2 Protein (SARS-CoV-2 S2) (P.1 - gamma) (His tag) (ABIN6992375)
Target
See all SARS-CoV-2 Spike S2 (SARS-CoV-2 S2) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- P.1 - gamma
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Purification tag / Conjugate
- This SARS-CoV-2 Spike S2 protein is labelled with His tag.
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Purpose
- SARS-CoV-2 S2 protein (T1027I, V1176F), His Tag
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Sequence
- AA 686-1213
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Characteristics
- SARS-CoV-2 S2 protein (T1027I, V1176F), His Tag is expressed from human 293 cells (HEK293). It contains AA Ser 686 - Pro 1213 (Accession # QHD43416.1). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (F817P/ A892P/ A899P/ A942P/ K986P/ V987P) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein. The T1027I/ V1176F mutations were identified in the SARS-CoV-2 variant (known as P.1) which emerged in Brazil.
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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- SARS-CoV-2 Spike S2 (SARS-CoV-2 S2)
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Alternative Name
- SARS-CoV-2 S2 protein
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Target Type
- Viral Protein
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Background
- The ongoing SARS-COV-2 pandemics has sickened 3.7 million people around the world, claiming over 1,000,000 lives. To deal with this global public health crisis, unprecedented efforts are being made to study the virus, SARS-CoV-2. At present, there are 193 new crown vaccine projects registered with the World Health Organization are being developed. To support these studies, ACRO has developed Mouse Anti-SARS-CoV-2 antibody IgG Serologic Assay kit.
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Molecular Weight
- 59.9 kDa
Target
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