DR3/LARD Protein (AA 25-199) (His tag)

Catalog No. ABIN7013178

Recombinant DR3/LARD protein expressed in HEK-293 Cells.

Quick Overview for DR3/LARD Protein (AA 25-199) (His tag) (ABIN7013178)

Target: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: >90 % as determined by SDS-PAGE.

Product Details

Protein Characteristics: AA 25-199

Purification tag / Conjugate: This DR3/LARD protein is labelled with His tag.

Purpose: Human DR3 / TNFRSF25 Protein, His Tag

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Storage: -20 °C

Target Details

Target: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Alternative Name: DR3 / TNFRSF25

Background: Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) is also known as Apo-3, Death receptor 3 (DDR3 or DR3), Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor TRAMP, Lymphocyte-associated receptor of death, Apo-3, which is a member of the TNF-receptor superfamily. TNFRSF25 is a homodimer protein, which can Interact strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling. TNFRSF25 is receptor for TNFSF12 / APO3L / TWEAK.

Molecular Weight: 20.9 kDa

NCBI Accession: NP_003781

Pathways: Apoptosis