CD39 Protein (AA 38-478) (His tag)
Quick Overview for CD39 Protein (AA 38-478) (His tag) (ABIN7013366)
Target
See all CD39 (ENTPD1) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 38-478
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Purification tag / Conjugate
- This CD39 protein is labelled with His tag.
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Characteristics
- Human CD39 / ENTPD1 Protein, His Tag (active enzyme)
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 1-510) protein (His tag)
custom-made ENTPD1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 1-510) protein (His tag)custom-made ENTPD1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 38-478) protein (His tag)ENTPD1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) proteinENTPD1 Origin: Human Host: HEK-293 Cells Synthetic Nanodisc
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 70-197) protein (His-IF2DI Tag)ENTPD1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 1-510) protein (GST tag)ENTPD1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (Active) protein (His tag)ENTPD1 Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 95 % as determined by SDS-PAGE Active
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 40-476) protein (Fc Tag)ENTPD1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 38-478) (Active) protein (mFc Tag)ENTPD1 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Tris and NaCl, pH 8.0
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Storage
- -20 °C
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- CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))
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Alternative Name
- CD39
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Background
- CD39 is also known as Ectonucleoside triphosphate diphosphohydrolase 1, ENTPD1, NTPDase 1, Ecto-ATPDase 1, in the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. NTPDase-1 was originally described as CD39, a B lymphocyte cell surface marker, but it is also present on the surface of natural killer cells, T cells, and some endothelial cells.Regulatory T cells(Tregs) mediate immunosuppression through multiple, non-redundant, cell-contact dependent and independent mechanisms, a growing body of evidence suggests an important role for the CD39-CD73-adenosine pathway. CD39 ectonucleotidase is the rate-limiting enzyme of a cascade leading to the generation of suppressive adenosine that alters CD4 and CD8 T cell and natural killer cell antitumor activities.
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Molecular Weight
- 52.3 kDa
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NCBI Accession
- NP_001767
Target
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