CCL19 Protein (AA 22-98)
Quick Overview for CCL19 Protein (AA 22-98) (ABIN7013431)
Target
See all CCL19 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 22-98
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Brand
- ActiveMax®
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Characteristics
- ActiveMax® Human CCL19 / MIP-3 beta Protein, Tag Free
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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- CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))
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Alternative Name
- CCL19
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Background
- C-C motif chemokine 19(CCL19) is as known as CK beta-11, ELC, MIP3B and SCYA19. May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
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Molecular Weight
- 8.8 kDa
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Pathways
- Positive Regulation of Immune Effector Process
Target
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