Mesothelin Protein (MSLN) (AA 298-600) (His tag)
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- Target See all Mesothelin (MSLN) Proteins
- Mesothelin (MSLN)
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 298-600
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Mesothelin protein is labelled with His tag.
- Characteristics
- Mouse Mesothelin / MSLN (298-600) Protein, His Tag (MALS verified)
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product MSLN Protein
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- Application Notes
- MALS verified
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
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- Target
- Mesothelin (MSLN)
- Alternative Name
- Mesothelin (MSLN Products)
- Background
- Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.
- Molecular Weight
- 36.0 kDa
- NCBI Accession
- NP_061345
- Pathways
- EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
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