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MASP2 Protein (Fc Tag)

MASP2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7092694
  • Target See all MASP2 Proteins
    MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))
    Protein Type
    Recombinant
    Origin
    • 6
    • 4
    • 3
    • 1
    Human
    Source
    • 6
    • 6
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This MASP2 protein is labelled with Fc Tag.
    Purpose
    Recombinant human MASP2 protein with N-terminal Human Fc tag
    Specificity
    HFc (Glu99-Ala330) MASP2 (Gln298-Ser684)
    Characteristics
    Extracellular Domain Protein
    Purification
    affinity purification
    Purity
    The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
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    Discover our top product MASP2 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))
    Alternative Name
    MASP2 (MASP2 Products)
    Synonyms
    MAP19 Protein, MASP-2 Protein, MASP1P1 Protein, sMAP Protein, MAp19 Protein, mannan binding lectin serine peptidase 2 Protein, mannan-binding lectin serine peptidase 2 Protein, MASP2 Protein, Masp2 Protein
    Background
    Synonymes: MAP19, MASP-2, MASP1P1, sMAP
    Description: This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
    Molecular Weight
    predicted molecular mass of 68.4 kDa after removal of the signal peptide.
    Gene ID
    10747
    UniProt
    O00187
    Pathways
    Complement System
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