MASP2 Protein (Fc Tag)
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- Target See all MASP2 Proteins
- MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MASP2 protein is labelled with Fc Tag.
- Purpose
- Recombinant human MASP2 protein with N-terminal Human Fc tag
- Specificity
- HFc (Glu99-Ala330) MASP2 (Gln298-Ser684)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product MASP2 Protein
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Mannan-Binding Lectin serine Peptidase 2 (MASP2) (AA 288-686) protein (His tag)
MASP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Mannan-Binding Lectin serine Peptidase 2 (MASP2) (AA 287-686) protein (His tag)MASP2 Origin: Cynomolgus Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Mannan-Binding Lectin serine Peptidase 2 (MASP2) (AA 287-685) protein (His tag)MASP2 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Mannan-Binding Lectin serine Peptidase 2 (MASP2) (AA 287-685) protein (His tag,Biotin)MASP2 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Mannan-Binding Lectin serine Peptidase 2 (MASP2) (AA 287-685) protein (His tag)MASP2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Mannan-Binding Lectin serine Peptidase 2 (MASP2) (AA 1-686) protein (GST tag)MASP2 Origin: Human Host: Wheat germ Recombinant ELISA, AP, AA, WB
Mannan-Binding Lectin serine Peptidase 2 (MASP2) (AA 445-683) (Active) protein (His tag)MASP2 Origin: Human Host: Escherichia coli (E. coli) > 97 % AcA, CC Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))
- Alternative Name
- MASP2 (MASP2 Products)
- Background
- This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
- Molecular Weight
- predicted molecular mass of 68.4 kDa after removal of the signal peptide.
- Gene ID
- 10747
- UniProt
- O00187
- Pathways
- Complement System
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