MASP2 Protein (AA 287-685) (Biotin,His tag)
Quick Overview for MASP2 Protein (AA 287-685) (Biotin,His tag) (ABIN7275295)
Target
See all MASP2 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 287-685
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Purification tag / Conjugate
- This MASP2 protein is labelled with Biotin,His tag.
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Purpose
- Biotinylated Rat MASP2 Protein (Primary Amine Labeling)
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Sequence
- Thr287-Phe685
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Characteristics
- Recombinant Biotinylated Rat MASP2 Protein (Primary Amine Labeling) is expressed from E.coli with His tag at the C-Terminus.It contains Thr287-Phe685.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Immobilized Narsoplimab, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Rat MASP2, His Tag with the EC50 of 19.3ng/ml determined by ELISA.,Biotinylated Rat MASP2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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Mannan-Binding Lectin serine Peptidase 2 (MASP2) (AA 288-686) (Active) protein (His tag)
MASP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Mannan-Binding Lectin serine Peptidase 2 (MASP2) (AA 287-686) (Active) protein (His tag)MASP2 Origin: Cynomolgus Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC Active
Mannan-Binding Lectin serine Peptidase 2 (MASP2) (AA 287-685) (Active) protein (His tag)MASP2 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Mannan-Binding Lectin serine Peptidase 2 (MASP2) (AA 1-686) protein (GST tag)MASP2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Mannan-Binding Lectin serine Peptidase 2 (MASP2) (AA 287-685) (Active) protein (His tag)MASP2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Bis-Tris PAGE Active
Mannan-Binding Lectin serine Peptidase 2 (MASP2) (AA 99-330) protein (Fc Tag)MASP2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Mannan-Binding Lectin serine Peptidase 2 (MASP2) (AA 445-683) (Active) protein (His tag)MASP2 Origin: Human Host: Escherichia coli (E. coli) > 97 % AcA, CC Active
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as 0.22μm filtered solution in 50 mM Tris, 200 mM NaCl ( pH 9.0).
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Storage
- -80 °C
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Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))
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Alternative Name
- MASP2
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Background
- Te MASP2 gene is located on the chromosome 1p36.23-31 and encodes two proteins, MASP-2 and Map198. Both the levels and function of MASP-2 are modulated by the single-nucleotide polymorphisms (SNPs) of the MASP2 gene. Te level of MASP-2 in plasma plays a dual role in the infection and progression of infectious diseases. Te defciency of MASP-2 in plasma has been associated with the susceptibility of HIV. By contrast, the overproduction of MASP-2 may increase the infammatory efect.
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Molecular Weight
- 46.7 kDa. Due to autocatalytic cleavage, the protein migrates to 15-20 kDa&25-30 kDa based on Bis-Tris PAGE result.
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UniProt
- A2VCV7
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Pathways
- Complement System
Target
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