Quick Overview for GP6 Protein (AA 21-267) (Fc Tag) (ABIN7092792)
Target
See all GP6 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 21-267
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Purification tag / Conjugate
- This GP6 protein is labelled with Fc Tag.
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Purpose
- Recombinant Human GP6 with C-terminal human Fc tag
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Specificity
- GP6 (Gln21-Lys267) hFc (Glu99-Ala330)
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Characteristics
- Extracellular Domain Protein
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Glycoprotein VI (Platelet) (GP6) (AA 21-267) protein (His tag)
GP6 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Glycoprotein VI (Platelet) (GP6) (AA 21-251) protein (His tag)GP6 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Glycoprotein VI (Platelet) (GP6) (AA 22-265) protein (His tag)GP6 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Glycoprotein VI (Platelet) (GP6) proteinGP6 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- GP6 (Glycoprotein VI (Platelet) (GP6))
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Alternative Name
- GP6
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Background
- This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
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Molecular Weight
- predicted molecular mass of 53.1 kDa after removal of the signal peptide. The apparent molecular mass of GP6-hFc is 55-100 kDa due to glycosylation.
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UniProt
- Q9HCN6
Target
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