TNFRSF8 Protein (AA 19-287) (Fc Tag)
Quick Overview for TNFRSF8 Protein (AA 19-287) (Fc Tag) (ABIN7092864)
Target
See all TNFRSF8 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 19-287
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Purification tag / Conjugate
- This TNFRSF8 protein is labelled with Fc Tag.
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Purpose
- Recombinant mouse CD30 protein with C-terminal human Fc tag
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Specificity
- Mouse CD30(Phe19-Gly287) hFc(Glu99-Ala330)
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Characteristics
- Extracellular Domain Protein
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Application Notes
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
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Comment
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The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please see Certificate of Analysis for specific instructions of reconstitution.
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))
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Alternative Name
- CD30
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Background
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Tnfrsf8,D1S166E,Ki,Ki-1
Receptor for TNFSF8/CD30L (PubMed:8543792). May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B (By similarity).[UniProtKB/Swiss-Prot Function] -
Molecular Weight
- predicted molecular mass of 54.4 kDa after removal of the signal peptide.The apparent molecular mass of mCD30-hFc is 55-100 kDa due to glycosylation.
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UniProt
- Q60846
Target
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