CD226 Protein (CD226) (His tag)
Quick Overview for CD226 Protein (CD226) (His tag) (ABIN7121305)
Target
See all CD226 ProteinsProtein Type
Origin
Source
Purity
Grade
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Purification tag / Conjugate
- This CD226 protein is labelled with His tag.
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Purpose
- Canine DNAM-1 / CD226 Protein, His Tag (SPR verified)
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Sequence
- Glu 32 - Gln 263
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Characteristics
- Canine DNAM-1, His Tag (DN1-C52H4) is expressed from human 293 cells (HEK293). It contains AA Glu 32 - Gln 263 (Accession # E2R115-1).
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Application Notes
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.2 kDa. The protein migrates as 36-50 kDa under reducing (R) condition due to glycosylation.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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Storage Comment
- -20°C
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- CD226
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Alternative Name
- DNAM-1 / CD226
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Background
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Synonyms: DNAM1,CD226,PTA1,
Description: DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2. -
Molecular Weight
- 28.2 kDa
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Target
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