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CD226 Protein (CD226) (His tag)

Recombinant CD226 protein expressed in HEK-293 Cells.
Catalog No. ABIN7121305

Quick Overview for CD226 Protein (CD226) (His tag) (ABIN7121305)

Target

See all CD226 Proteins
CD226

Protein Type

Recombinant

Origin

  • 19
  • 5
  • 2
  • 1
Dog

Source

  • 16
  • 5
  • 3
  • 2
  • 1
HEK-293 Cells

Purity

>95 % as determined by SDS-PAGE.

Grade

SPR verified
  • Purification tag / Conjugate

    This CD226 protein is labelled with His tag.

    Purpose

    Canine DNAM-1 / CD226 Protein, His Tag (SPR verified)

    Sequence

    Glu 32 - Gln 263

    Characteristics

    Canine DNAM-1, His Tag (DN1-C52H4) is expressed from human 293 cells (HEK293). It contains AA Glu 32 - Gln 263 (Accession # E2R115-1).

    Endotoxin Level

    Less than 1.0 EU per μg by the LAL method.
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  • Application Notes

    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.2 kDa. The protein migrates as 36-50 kDa under reducing (R) condition due to glycosylation.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4

    Storage

    -20 °C

    Storage Comment

    -20°C
  • Target

    CD226

    Alternative Name

    DNAM-1 / CD226

    Background

    Synonyms: DNAM1,CD226,PTA1,
    Description: DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.

    Molecular Weight

    28.2 kDa

    Pathways

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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