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Interleukin 17a Protein (His tag)

This Recombinant Interleukin 17a protein is expressed in HEK-293 Cells.
Catalog No. ABIN7121397
$480.00
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Quick Overview for Interleukin 17a Protein (His tag) (ABIN7121397)

Target

See all Interleukin 17a (IL17A) Proteins
Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Protein Type

Recombinant

Origin

  • 19
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Dog

Source

  • 12
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HEK-293 Cells

Purity

>90 % as determined by SDS-PAGE.
  • Purification tag / Conjugate

    This Interleukin 17a protein is labelled with His tag.

    Purpose

    Canine IL-17A / CTLA-8 Protein, His Tag

    Sequence

    Gly 26 - Ala 155

    Characteristics

    Canine IL-17A, His Tag (ILA-C52H7) is expressed from human 293 cells (HEK293). It contains AA Gly 26 - Ala 155 (Accession # C6L8D7-1).

    Endotoxin Level

    Less than 1.0 EU per μg by the LAL method.
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  • Application Notes

    This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 17.0 kDa. The protein migrates as 18 kDa and 22 kDa under reducing (R) condition due to glycosylation.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4

    Storage

    -20 °C

    Storage Comment

    -20°C
  • Target

    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

    Alternative Name

    IL-17A / CTLA-8

    Background

    Synonyms: IL-17A,Interleukin-17A,CTLA-8,IL-17,
    Description: Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

    Molecular Weight

    17.0 kDa

    NCBI Accession

    NM_001165878
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