Interleukin 17a Protein (His tag)
Quick Overview for Interleukin 17a Protein (His tag) (ABIN7121397)
Target
See all Interleukin 17a (IL17A) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This Interleukin 17a protein is labelled with His tag.
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Purpose
- Canine IL-17A / CTLA-8 Protein, His Tag
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Sequence
- Gly 26 - Ala 155
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Characteristics
- Canine IL-17A, His Tag (ILA-C52H7) is expressed from human 293 cells (HEK293). It contains AA Gly 26 - Ala 155 (Accession # C6L8D7-1).
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Application Notes
- This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 17.0 kDa. The protein migrates as 18 kDa and 22 kDa under reducing (R) condition due to glycosylation.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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Storage Comment
- -20°C
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- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
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Alternative Name
- IL-17A / CTLA-8
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Background
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Synonyms: IL-17A,Interleukin-17A,CTLA-8,IL-17,
Description: Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. -
Molecular Weight
- 17.0 kDa
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NCBI Accession
- NM_001165878
Target
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