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Interleukin 17a Protein (His tag)

This Recombinant Interleukin 17a protein is expressed in HEK-293 Cells.
Catalog No. ABIN7121397

Quick Overview for Interleukin 17a Protein (His tag) (ABIN7121397)

Target

See all Interleukin 17a (IL17A) Proteins
Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Protein Type

Recombinant

Origin

  • 22
  • 13
  • 3
  • 2
  • 2
  • 1
  • 1
Dog

Source

  • 15
  • 12
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
HEK-293 Cells

Purity

>90 % as determined by SDS-PAGE.
  • Purification tag / Conjugate

    This Interleukin 17a protein is labelled with His tag.

    Purpose

    Canine IL-17A / CTLA-8 Protein, His Tag

    Sequence

    Gly 26 - Ala 155

    Characteristics

    Canine IL-17A, His Tag (ILA-C52H7) is expressed from human 293 cells (HEK293). It contains AA Gly 26 - Ala 155 (Accession # C6L8D7-1).

    Endotoxin Level

    Less than 1.0 EU per μg by the LAL method.
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  • Application Notes

    This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 17.0 kDa. The protein migrates as 18 kDa and 22 kDa under reducing (R) condition due to glycosylation.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4

    Storage

    -20 °C

    Storage Comment

    -20°C
  • Target

    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

    Alternative Name

    IL-17A / CTLA-8

    Background

    Synonyms: IL-17A,Interleukin-17A,CTLA-8,IL-17,
    Description: Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

    Molecular Weight

    17.0 kDa

    NCBI Accession

    NM_001165878
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