IFN-alpha/beta R1 protein (His tag)

Catalog No. ABIN7121489

This Recombinant protein is produced in HEK-293 Cells.

Quick Overview for IFN-alpha/beta R1 protein (His tag) (ABIN7121489)

Target: IFN-alpha/beta R1

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: >90 % as determined by SDS-PAGE.

Product Details

Purification tag / Conjugate: His tag

Purpose: Mouse IFN-alpha / beta R1 Protein, His Tag

Sequence: Glu 27 - Thr 429

Characteristics: Mouse IFN-alpha / beta R1, His Tag (IF1-M5225) is expressed from human 293 cells (HEK293). It contains AA Glu 27 - Thr 429 (Accession # P33896-1).

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Application Notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 47.6 kDa. The protein migrates as 57-66 kDa under reducing (R) condition due to glycosylation.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Storage: -20 °C

Storage Comment: -20°C

Target Details

Target: IFN-alpha/beta R1

Alternative Name: IFN-alpha / beta R1

Background: Synonyms: IFNAR1,IFNAR,CRF2-1,IFN-R-1,IFNAR-1,
Description: Interferon alpha/beta receptor 1 ( IFNAR1) is also known as Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1 (CRF2-1), Type I interferon receptor 1, IFNAR, which belongs to the type II cytokine receptor family. IFNAR1 /IFNAR contains four fibronectin type-III domains. IFNAR1 associates with IFNAR2 to form the type I interferon receptor. IFNAR1 is receptor for interferons alpha and beta. IFNAR1 can transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.

Molecular Weight: 47.6 kDa

NCBI Accession: NP_034638