Interleukin 17a Protein
Quick Overview for Interleukin 17a Protein (ABIN7199556)
Target
See all Interleukin 17a (IL17A) ProteinsProtein Type
Origin
Source
Purity
Grade
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Purpose
- Human IL-17A / CTLA-8 Protein, Tag Free (MALS verified)
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Sequence
- Gly 24 - Ala 155
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Characteristics
- Human IL17A, Tag Free (ILA-H5219) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Ala 155 (Accession # Q16552-1).
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Interleukin 17A (IL17A) (AA 24-155) protein (His tag)
IL17A Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 17A (IL17A) (AA 24-155) protein (His-Avi Tag,Biotin)IL17A Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 17A (IL17A) (AA 24-155) protein (His-Avi Tag)IL17A Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 92 % as determined by HPLC
Interleukin 17A (IL17A) (AA 26-158) protein (His-Avi Tag,Biotin)IL17A Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 17A (IL17A) (Active) protein (His tag)IL17A Origin: Cynomolgus Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE. Active
Interleukin 17A (IL17A) (Active) protein (His tag)IL17A Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE Active
Interleukin 17A (IL17A) (AA 26-158) protein (His-Avi Tag)IL17A Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 17A (IL17A) (AA 24-155) (Active) protein (His tag)IL17A Origin: Cynomolgus Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 17A (IL17A) (AA 24-155) (Active) protein (His tag,AVI tag,Biotin)IL17A Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 17A (IL17A) (AA 24-155) protein (His tag)IL17A Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
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Application Notes
- This protein carries no "tag". The protein has a calculated MW of 15.1 kDa. As a result of glycosylation, the protein migrates as 16 kDa, 17 kDa and 19 kDa under reducing (R) condition, and 27-34 kDa under non-reducing (NR) condition .
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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Storage Comment
- -20°C
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- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
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Alternative Name
- IL-17A / CTLA-8
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Background
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Synonyms: IL-17A,Interleukin-17A,CTLA-8,IL-17,
Description: Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. -
Molecular Weight
- 15.1 kDa
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NCBI Accession
- NP_002181
Target
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