Quick Overview for ANGPTL4 Protein (Fc Tag) (ABIN7320470)
Target
See all ANGPTL4 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This ANGPTL4 protein is labelled with Fc Tag.
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Purpose
- Recombinant Mouse ANGPTL4 Protein (Fc Tag)
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Sequence
- Lys167-Ser410
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Characteristics
- Recombinant Mouse Angiopoietin Like protein 4 is produced by our Mammalian expression system and the target gene encoding Lys167-Ser410 is expressed with a Fc tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Angiopoietin-Like 4 (ANGPTL4) (AA 166-406) protein (His tag)
ANGPTL4 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Angiopoietin-Like 4 (ANGPTL4) (AA 164-406) protein (His tag)ANGPTL4 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Angiopoietin-Like 4 (ANGPTL4) (AA 26-406) protein (GST tag)ANGPTL4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Angiopoietin-Like 4 (ANGPTL4) protein (His tag)ANGPTL4 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Angiopoietin-Like 4 (ANGPTL4) (AA 168-410) protein (His tag)ANGPTL4 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Angiopoietin-Like 4 (ANGPTL4) (AA 26-130) protein (GST tag)ANGPTL4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))
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Alternative Name
- ANGPTL4
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Background
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Background: Angiopoietin-related protein 4(ANGPTL4)is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.
Synonym: Angiopoietin-related protein 4,425O18-1,Angiopoietin-like protein 4,Fasting-induced adipose factor,Hepatic fibrinogen/angiopoietin-related protein,HFARP,Secreted protein Bk89,Angptl4,Farp, Fiaf, Ng27
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Molecular Weight
- 54.6 kDa
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UniProt
- Q9Z1P8
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Pathways
- Regulation of Lipid Metabolism by PPARalpha
Target
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