APOA4 Protein (His tag)
Quick Overview for APOA4 Protein (His tag) (ABIN7319239)
Target
See all APOA4 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This APOA4 protein is labelled with His tag.
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Purpose
- Recombinant Human APOA4 Protein (His Tag)
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Sequence
- Glu21-Ser396
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Characteristics
- Recombinant Human Apolipoprotein A-IV is produced by our Mammalian expression system and the target gene encoding Glu21-Ser396 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- APOA4 (Apolipoprotein A-IV (APOA4))
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Alternative Name
- APOA4
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Background
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Background: Apolipoprotein A4 (APOA4) is a secreted protein that belongs to the apolipoprotein A1/A4/E family. Apoa-IV is a major component of HDL and chylomicrons. APOA4 is secreted into circulation on the surface of newly synthesized chylomicron particles. APOA4 play a role in the regulation of appetite and satiety in rodent models. APOA4 involved in chylomicrons and VLDL secretion and catabolism and required for efficient activation of lipoprotein lipase by ApoC-II. In addition, APOA4 is a potent activator of lecithin-cholesterol acyltransferase in vitro.
Synonym: Apolipoprotein A-IV, Apo-AIV, ApoA-IV, Apolipoprotein A4, APOA4
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Molecular Weight
- 44.4 kDa
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UniProt
- P06727
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Pathways
- Lipid Metabolism
Target
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