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NPR3 Protein (Fc Tag)

NPR3 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319905
  • Target See all NPR3 Proteins
    NPR3 (Atrial Natriuretic Peptide Receptor 3 (NPR3))
    Protein Type
    Recombinant
    Origin
    • 6
    • 3
    • 3
    • 1
    • 1
    Human
    Source
    • 4
    • 3
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This NPR3 protein is labelled with Fc Tag.
    Purpose
    Recombinant Human NPRC/NPR3 (C-Fc)
    Sequence
    Thr24-Glu481
    Characteristics
    Recombinant Human Atrial Natriuretic Peptide Receptor 3 is produced by our Mammalian expression system and the target gene encoding Thr24-Glu481 is expressed with a Fc tag at the C-terminus.
    Purity
    >95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product NPR3 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    NPR3 (Atrial Natriuretic Peptide Receptor 3 (NPR3))
    Alternative Name
    NPRC/NPR3 (NPR3 Products)
    Synonyms
    B430320C24Rik Protein, C81222 Protein, NPR-C Protein, lgj Protein, stri Protein, ANP-C Protein, ANPR-C Protein, ANPRC Protein, C5orf23 Protein, GUCY2B Protein, NPRC Protein, ANP-CR Protein, natriuretic peptide receptor 3 Protein, Npr3 Protein, NPR3 Protein
    Background

    Background: Atrial Natriuretic Peptide Receptor-3 (NPR3), also known as NPRC or ANPR-C, is one of the three natriuretic peptide receptors, is a type I transmembrane glycoprotein. The natriuretic system is key to the maintenance of vascular tone and cardiovascular homeostasis. Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. Osteocrin was found to be a specific ligand to NPR3. NPR3 is necessary for Osteocrin to regulate femoral, tibial, and metatarsal bone elongation.

    Synonym: ANP-C, ANPR-C, NPR3, NPRC, NPR-C,ANPRC, C5orf23

    Molecular Weight
    77.5 kDa
    UniProt
    P17342
    Pathways
    cAMP Metabolic Process
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