BCL2L1 Protein (His tag)
Quick Overview for BCL2L1 Protein (His tag) (ABIN7319690)
Target
See all BCL2L1 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This BCL2L1 protein is labelled with His tag.
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Purpose
- Recombinant Human BCL2L1/Bcl-XL Protein (His Tag)
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Sequence
- Met1-Arg212
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Characteristics
- Recombinant Human BCL2L1 is produced by our E.coli expression system and the target gene encoding Met1-Arg212 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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BCL2-Like 1 (BCL2L1) (AA 1-233) protein (His tag)
custom-made BCL2L1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
BCL2-Like 1 (BCL2L1) (AA 1-233) protein (His tag)custom-made BCL2L1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
BCL2-Like 1 (BCL2L1) (AA 1-233) protein (GST tag)BCL2L1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
BCL2-Like 1 (BCL2L1) (AA 1-209) protein (His-IF2DI Tag)BCL2L1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
BCL2-Like 1 (BCL2L1) (AA 1-212) protein (His-IF2DI Tag)BCL2L1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
BCL2-Like 1 (BCL2L1) (AA 1-212) protein (Fc Tag)BCL2L1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
BCL2-Like 1 (BCL2L1) (AA 1-212) (Active) protein (His tag)BCL2L1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE Active
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM HEPES, 50 mM KCl, 20 % Glycerol, pH 7.5.
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- BCL2L1 (BCL2-Like 1 (BCL2L1))
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Alternative Name
- BCL2L1/Bcl-XL
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Background
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Background: Bcl-2-Like Protein 1 (BCL2L1) is a member of the Bcl-2 family. BCL2L1 is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. BCL2L1 is a mitochondrial membrane protein. BCL2L1 contains four motifs, BH1, BH2 and BH4. The BH4 motif is required for anti-apoptotic activity. The BH1 and BH2 motifs are required for both heterodimerization with other Bcl-2 family members and for repression of cell death. BCL2L1 regulates cell death by blocking the voltage-dependent anion channnel (VDAC) and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. In addition, BCL2L1 promotes apoptosis.
Synonym: Bcl-2-Like Protein 1, Bcl2-L-1, Apoptosis Regulator Bcl-X, Bcl-X,bcl-xL,BCL-XL/S,bcl-xS,BCL2L,BCLX,BCLXL,BCLXS,PPP1R52
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Molecular Weight
- 24.85 kDa
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UniProt
- Q07817
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Pathways
- Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
Target
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