Biglycan Protein (BGN) (Fc Tag)
Quick Overview for Biglycan Protein (BGN) (Fc Tag) (ABIN7320153)
Target
See all Biglycan (BGN) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This Biglycan protein is labelled with Fc Tag.
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Purpose
- Recombinant Mouse Biglycan/BGN Protein (Fc Tag)
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Sequence
- Met1-Lys369
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Characteristics
- A DNA sequence encoding the mouse BGN (Met1-Lys369) was expressed with the Fc region of human IgG1 at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biglycan (BGN) (AA 1-368) protein (GST tag)
BGN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Biglycan (BGN) (AA 38-368) (Active) protein (His tag)BGN Origin: Human Host: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. SDS, WB, Imm, ELISA, AcA Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile PBS, pH 7.4
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Biglycan (BGN)
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Alternative Name
- Biglycan/BGN
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Background
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Background: Biglycan, also known as PG-S1 and BGN, is a a small leucine-rich repeat proteoglycan (SLRP). It can be detected in a variety of extracellular matrix tissues, including bone, cartilage and tendon. Biglycan consists of a protein core containing leucine-rich repeat regions and two glycosaminoglycan (GAG) chains consisting of either chondroitin sulfate (CS) or dermatan sulfate (DS). Non-glycanated forms of biglycan (no GAG chains) increase with age in human articular cartilage. Biglycan interacts with collagen, both via the core protein and GAG chains. Biglycan plays a role in the mineralisation of bone. Biglycan core protein binds to the growth factors BMP-4 and influences its bioactivity.
Synonym: BG,DSPG1,PG-S1,PGI,SLRR1A
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Molecular Weight
- 66.5 kDa
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NCBI Accession
- NP_031568
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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