Quick Overview for CLEC3B Protein (His tag) (ABIN7320183)
Target
See all CLEC3B ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This CLEC3B protein is labelled with His tag.
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Purpose
- Recombinant Mouse CLEC3B/Tetranectin Protein (His Tag)
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Sequence
- Met 1-Val 202
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Characteristics
- A DNA sequence encoding the mouse CLEC3B (P43025) (Met 1-Val 202) was expressed, with a C-terminal polyhistidinetag.
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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C-Type Lectin Domain Family 3, Member B (CLEC3B) (AA 1-202) protein (GST tag)
CLEC3B Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
C-Type Lectin Domain Family 3, Member B (CLEC3B) protein (Myc-DYKDDDDK Tag)CLEC3B Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile PBS, pH 7.4
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CLEC3B (C-Type Lectin Domain Family 3, Member B (CLEC3B))
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Alternative Name
- CLEC3B/Tetranectin
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Background
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Background: Tetranectin (TN), also known as C-type lectin domain family 3, member B (CLEC3B) is a member of the C-type lectin Family. It is plasminogen kringle 4 binding protein and regulates fibrinolysis and proteolytic processes via binding to plasminogen. Tetranectin has been suggested to play a role in tissue remodeling, due to its ability to stimulate plasminogen activation and its expression in developing tissues such as developing bone and muscle. Tetranectin enhances plasminogen activation by a tissue-type plasminogen activator so that it has been suggested to play a role in tissue remodeling. Tetranectin may play a role in the wound healing process. Tetranectin may play a role in neurological diseases and may serve as a diagnostic aid in multiple sclerosis (MS). Tetranectin was found significantly under-expressed in both serum and saliva of metastatic oral squamous cell carcinoma (OSCC) compared to primary OSCC. Tetranectin is thought to enhance proteolytic processes enabling tumor cells to invade and metastasize.
Synonym: Tna
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Molecular Weight
- 20.7 kDa
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UniProt
- P43025
Target
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