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CLEC3B Protein (His tag)

CLEC3B Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Catalog No. ABIN7320183
  • Target See all CLEC3B Proteins
    CLEC3B (C-Type Lectin Domain Family 3, Member B (CLEC3B))
    Protein Type
    Recombinant
    Origin
    • 7
    • 1
    • 1
    Mouse
    Source
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CLEC3B protein is labelled with His tag.
    Purpose
    Recombinant Mouse CLEC3B/Tetranectin Protein (His Tag)
    Sequence
    Met 1-Val 202
    Characteristics
    A DNA sequence encoding the mouse CLEC3B (P43025) (Met 1-Val 202) was expressed, with a C-terminal polyhistidinetag.
    Purity
    > 95 % as determined by SDS-PAGE
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product CLEC3B Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CLEC3B (C-Type Lectin Domain Family 3, Member B (CLEC3B))
    Alternative Name
    CLEC3B/Tetranectin (CLEC3B Products)
    Synonyms
    Tna Protein, clec3b Protein, tetn Protein, TN Protein, TNA Protein, C-type lectin domain family 3, member B Protein, C-type lectin domain family 3 member B Protein, tetranectin Protein, C-type lectin domain family 3, member b Protein, Clec3b Protein, clec3b Protein, CLEC3B Protein, tetn Protein
    Background

    Background: Tetranectin (TN), also known as C-type lectin domain family 3, member B (CLEC3B) is a member of the C-type lectin Family. It is plasminogen kringle 4 binding protein and regulates fibrinolysis and proteolytic processes via binding to plasminogen. Tetranectin has been suggested to play a role in tissue remodeling, due to its ability to stimulate plasminogen activation and its expression in developing tissues such as developing bone and muscle. Tetranectin enhances plasminogen activation by a tissue-type plasminogen activator so that it has been suggested to play a role in tissue remodeling. Tetranectin may play a role in the wound healing process. Tetranectin may play a role in neurological diseases and may serve as a diagnostic aid in multiple sclerosis (MS). Tetranectin was found significantly under-expressed in both serum and saliva of metastatic oral squamous cell carcinoma (OSCC) compared to primary OSCC. Tetranectin is thought to enhance proteolytic processes enabling tumor cells to invade and metastasize.

    Synonym: Tna

    Molecular Weight
    20.7 kDa
    UniProt
    P43025
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