Cadherin 13 Protein (CDH13)

Catalog No. ABIN7321153

Recombinant Cadherin 13 protein expressed in HEK-293 Cells.

Quick Overview for Cadherin 13 Protein (CDH13) (ABIN7321153)

Target: Cadherin 13 (CDH13)

Protein Type: Recombinant

Origin: Rat

Source: HEK-293 Cells

Purity: > 90 % as determined by SDS-PAGE

Product Details

Purpose: Recombinant Rat Cadherin-13/CDH13 Protein

Sequence: Met1-Ala692

Characteristics: A DNA sequence encoding the rat CDH13 (NP_620244.1)(Met1-Ala692) was expressed with six amino acids (LEVLFQ) at the C-terminus.

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: Cadherin 13 (CDH13)

Alternative Name: Cadherin-13/CDH13

Background:

Background: CDH13, also known as cadherin-13 and H Cadherin, is a member of the cadherin superfamily. CDH13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. CDH13 is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. CDH13 gene is hypermethylated in many types of cancer.

Synonym: CDH13

Molecular Weight: 74.3 kDa

NCBI Accession: NP_620244

Pathways: EGFR Signaling Pathway, Cell-Cell Junction Organization