Carbonic Anhydrase 14 (CAR14) protein (His tag)

Catalog No. ABIN7320476

This Recombinant Carbonic Anhydrase 14 protein is produced in Escherichia coli (E. coli).

Quick Overview for Carbonic Anhydrase 14 (CAR14) protein (His tag) (ABIN7320476)

Target: Carbonic Anhydrase 14 (CAR14)

Protein Type: Recombinant

Origin: Mouse

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by SDS-PAGE

Product Details

Purification tag / Conjugate: His tag

Purpose: Recombinant Mouse Carbonic Anhydrase 14/Car14 Protein (His Tag)

Sequence: Ala16-Met290

Characteristics: Recombinant Mouse Carbonic anhydrase 14 is produced by our E.coli expression system and the target gene encoding Ala16-Met290 is expressed with a 6His tag at the N-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Target Details

Target: Carbonic Anhydrase 14 (CAR14)

Alternative Name: Carbonic Anhydrase 14/Car14

Background:

Background: Mouse Ca14,also known as Carbonic anhydrase 14,is a member of large family of zinc metalloenzymes .It could catalyze reversible hydration of carbon dioxide. The reaction is fundamental to many processes such as respiration, renal tubular acidification and bone resorption. Fifteen CA isoforms have been reported so far. They have different patterns of tissue-specific expression and physiologic roles. Some CAs may serve as markers for tumors and hypoxia. CA XIV is a polypeptide consisting of an extracellular N-terminal catalytic domain, a membrane-spanning segment and a short intracellular C- terminal segment with several potential phosphorylation sites. A subset of CAs lack CA activity due to point mutations but retain esterase function. CA14 is widely expressed in the central nervous system

Synonym: Carbonic Anhydrase 14, Carbonate Dehydratase XIV, Carbonic Anhydrase XIV, CA-XIV, CA14,Ca14,Car14,Catm

Molecular Weight: 32.3 kDa

UniProt: Q9WVT6