CA4 Protein (AA 18-277) (His tag)
Quick Overview for CA4 Protein (AA 18-277) (His tag) (ABIN7320479)
Target
See all CA4 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 18-277
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Purification tag / Conjugate
- This CA4 protein is labelled with His tag.
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Purpose
- Recombinant Mouse Carbonic Anhydrase 4/CA4 Protein (aa 18-277, His Tag)
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Sequence
- Glu18-Ser277
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Characteristics
- Recombinant Mouse Carbonic anhydrase 4 is produced by our Mammalian expression system and the target gene encoding Glu18-Ser277 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- CA4 (Carbonic Anhydrase IV (CA4))
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Alternative Name
- Carbonic Anhydrase 4/CA4
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Background
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Background: Carbonic anhydrase 4(CA4) is an enzyme that belongs to the alpha-carbonic anhydrase family. CA4 consists of a signal peptide (residues1-17), an ectodomain (residues18-277) and a propeptide (residues278-305), which is removed in the mature form. it is predominantly expressed in the embryo. CA4 can catalyzes the reversible reaction of CO2+H2O=HCO3-+H+, and stimulates the sodium/bicarbonate transporter activity of SLC4A4. Studies have shown that this protein have a role in inherited renal abnormalities of bicarbonate transport. Alpha-carbonic anhydrase family participate in avariety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor. They show extensive diversity in tissue is attribution and in their sub cellular localization.
Synonym: CA4,CAIV,CA-IV,Car4,Carbonate dehydratase IV,carbonic anhydrase 4,carbonic anhydrase IVRP17,carbonic dehydratase IV,EC4.2.1.1,retinitis pigmentosa 17,RP17
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Molecular Weight
- 30.5 kDa
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UniProt
- Q64444
Target
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