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CA4 Protein (AA 18-277) (His tag)

This Recombinant CA4 protein is expressed in Human Cells.
Catalog No. ABIN7320479

Quick Overview for CA4 Protein (AA 18-277) (His tag) (ABIN7320479)

Target

See all CA4 Proteins
CA4 (Carbonic Anhydrase IV (CA4))

Protein Type

Recombinant

Origin

  • 6
  • 4
  • 3
  • 1
  • 1
Mouse

Source

  • 7
  • 3
  • 2
  • 2
  • 1
Human Cells

Purity

> 95 % as determined by SDS-PAGE
  • Protein Characteristics

    AA 18-277

    Purification tag / Conjugate

    This CA4 protein is labelled with His tag.

    Purpose

    Recombinant Mouse Carbonic Anhydrase 4/CA4 Protein (aa 18-277, His Tag)

    Sequence

    Glu18-Ser277

    Characteristics

    Recombinant Mouse Carbonic anhydrase 4 is produced by our Mammalian expression system and the target gene encoding Glu18-Ser277 is expressed with a 6His tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Frozen, Liquid

    Buffer

    Supplied as a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.

    Storage

    -20 °C

    Storage Comment

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target

    CA4 (Carbonic Anhydrase IV (CA4))

    Alternative Name

    Carbonic Anhydrase 4/CA4

    Background

    Background: Carbonic anhydrase 4(CA4) is an enzyme that belongs to the alpha-carbonic anhydrase family. CA4 consists of a signal peptide (residues1-17), an ectodomain (residues18-277) and a propeptide (residues278-305), which is removed in the mature form. it is predominantly expressed in the embryo. CA4 can catalyzes the reversible reaction of CO2+H2O=HCO3-+H+, and stimulates the sodium/bicarbonate transporter activity of SLC4A4. Studies have shown that this protein have a role in inherited renal abnormalities of bicarbonate transport. Alpha-carbonic anhydrase family participate in avariety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor. They show extensive diversity in tissue is attribution and in their sub cellular localization.

    Synonym: CA4,CAIV,CA-IV,Car4,Carbonate dehydratase IV,carbonic anhydrase 4,carbonic anhydrase IVRP17,carbonic dehydratase IV,EC4.2.1.1,retinitis pigmentosa 17,RP17

    Molecular Weight

    30.5 kDa

    UniProt

    Q64444
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