CPA1 Protein (His tag)
Quick Overview for CPA1 Protein (His tag) (ABIN7318242)
Target
See all CPA1 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This CPA1 protein is labelled with His tag.
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Purpose
- Recombinant Human Carboxypeptidase A1/CPA1 Protein (His Tag)
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Sequence
- Lys17-Tyr419
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Characteristics
- Recombinant Human Carboxypeptidase A1 is produced by our Mammalian expression system and the target gene encoding Lys17-Tyr419 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150mm NaCl, pH 7.5.
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- CPA1 (Carboxypeptidase A1 (Pancreatic) (CPA1))
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Alternative Name
- Carboxypeptidase A1/CPA1
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Background
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Background: Carboxypeptidase A1 (CPA1) is secreted as a pancreatic peptidase that comes from the precursor form of inactive procarboxypeptidase. CPA1 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. It has a free C-terminal carboxyl group, with the preference of residues with aromatic or branched aliphatic side chains. CPA1 cleaves the C-terminal amide or ester bond of peptides and involves in zymogen inhibition. Three different forms of human pancreatic procarboxypeptidase A have been isolated. In contrast to procarboxypeptidase B which was always secreted by the pancreas as a monomer, procarboxypeptidase A occurs as a monomer and/or associated to one or two functionally different proteins, such as zymogen E.
Synonym: Carboxypeptidase A1, CPA1, CPA
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Molecular Weight
- 46.6 kDa
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UniProt
- P15085
Target
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