Quick Overview for DCL1 Protein (Fc Tag) (ABIN7321088)
Target
See all DCL1 (CD302) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This DCL1 protein is labelled with Fc Tag.
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Purpose
- Recombinant Rat CD302/CLEC13A Protein (Fc Tag)
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Sequence
- Met1-His165
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Characteristics
- A DNA sequence encoding the rat CD302 (Met1-His165) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method
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CD302 (CD302) (AA 1-170) protein (GST tag)
CD302 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
CD302 (CD302) protein (His tag)CD302 Origin: Mouse Host: HEK-293 Cells Recombinant > 93 % as determined by SDS-PAGE
CD302 (CD302) protein (Fc Tag)CD302 Origin: Mouse Host: HEK-293 Cells Recombinant > 93 % as determined by SDS-PAGE
CD302 (CD302) protein (Myc-DYKDDDDK Tag)CD302 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
CD302 (CD302) proteinCD302 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile PBS, pH 7.4
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- DCL1 (CD302) (CD302)
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Alternative Name
- CD302/CLEC13A
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Background
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Background: CD302/CLEC13A (C-type lectin domain family 13 member A), also known as C-type lectin receptor DCL-1, is a type I transmembrane C-type lectin DCL-1/CD302. DCL-1 protein was highly conserved among the human, mouse, and rat orthologs. DCL-1 ectodomain contains only one CRD, whereas other type I transmembrane C-type lectins contain more than one domain (e.g. selectins and MMR). DCL-1 CP contains several putative motifs, including a Tyr-based internalization, a cluster of acidic amino acids, and Ser and Tyr phosphorylation motifs, suggesting that DCL-1 CP mediates not only endocytosis and late endosome targeting but also signaling. DCL-1 may be another cell/matrix adhesion receptor integrated in cell adhesion complexes and that DCL-1 dysfunction may affect APC adhesion and migration, causing suppression of APC function.
Synonym: CD302
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Molecular Weight
- 43.7 kDa
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NCBI Accession
- NP_001013938
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Pathways
- Regulation of Actin Filament Polymerization
Target
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