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CD38 Protein (Fc Tag)

This Recombinant CD38 protein is produced in Human Cells.
Catalog No. ABIN7320968

Quick Overview for CD38 Protein (Fc Tag) (ABIN7320968)

Target

See all CD38 Proteins
CD38

Protein Type

Recombinant

Origin

  • 26
  • 10
  • 5
  • 2
  • 1
Cynomolgus

Source

  • 18
  • 10
  • 6
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human Cells

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This CD38 protein is labelled with Fc Tag.

    Purpose

    Recombinant Cynomolgus CD38/ADP-ribosyl Cyclase 1 Protein (Fc Tag)

    Sequence

    Leu44-Ile301

    Characteristics

    Recombinant Cynomolgus CD38 is produced by our Mammalian expression system and the target gene encoding Leu44-Ile301 is expressed with a Fc tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    CD38

    Alternative Name

    CD38/ADP-ribosyl Cyclase 1

    Background

    Background: CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.

    Synonym: ADP-ribosyl cyclase 1, cyclic ADP-ribose hydrolase,CD38,T10

    Molecular Weight

    57 kDa

    UniProt

    Q5VAN0
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