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CD38 Protein (His tag)

This Recombinant CD38 protein is expressed in Human Cells.
Catalog No. ABIN7320976
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Quick Overview for CD38 Protein (His tag) (ABIN7320976)

Target

See all CD38 Proteins
CD38

Protein Type

Recombinant

Origin

  • 23
  • 11
  • 6
  • 3
  • 1
Cynomolgus

Source

  • 15
  • 10
  • 6
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human Cells

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This CD38 protein is labelled with His tag.

    Purpose

    Recombinant Cynomolgus CD38/ADP-ribosyl Cyclase 1 Protein (His Tag)

    Sequence

    Leu44-Ile301

    Characteristics

    Recombinant Cynomolgus CD38 is produced by our Mammalian expression system and the target gene encoding Leu44-Ile301 is expressed with a 6His tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    CD38

    Alternative Name

    CD38/ADP-ribosyl Cyclase 1

    Background

    Background: CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.

    Synonym: ADP-ribosyl cyclase 1, cyclic ADP-ribose hydrolase,CD38,T10

    Molecular Weight

    30.9 kDa

    UniProt

    Q5VAN0
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