Quick Overview for CD6 Protein (CD6) (His tag) (ABIN7320847)
Target
See all CD6 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This CD6 protein is labelled with His tag.
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Purpose
- Recombinant Mouse CD6/TP120 Protein (His Tag)
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Sequence
- Leu18-Gly396
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Characteristics
- Recombinant Mouse CD6 antigen is produced by our Mammalian expression system and the target gene encoding Leu18-Gly396 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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CD6 (CD6) (AA 18-402) (Active) protein (His tag)
CD6 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD6 (CD6) (AA 308-400) protein (GST tag)CD6 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
CD6 (CD6) (AA 18-398) protein (His tag)CD6 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
CD6 (CD6) (Active) protein (His tag)CD6 Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
CD6 (CD6) (Active) protein (His tag)CD6 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
CD6 (CD6) (Active) protein (Fc Tag)CD6 Origin: Mouse Host: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE Active
CD6 (CD6) (Active) protein (Fc Tag)CD6 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE. Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD6
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Alternative Name
- CD6/TP120
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Background
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Background: CD6 is a member of the group B scavenger receptor cysteinerich(SRCR) superfamily. CD6 is a type I membrane glycoprotein and contains three extracellularSRCR domains. CD6 is expressed at low levels on immature thymocytes and at high levels on mature thymocytes. The majority of peripheral blood T cells, a subsetof B cells, and a subset of neuronal cells express CD6. Mouse CD6 is a 626 amino acid (aa) protein with a 24 aa sequence, a 372 aa extracellular domain, and a204 aa cytoplasmic region. The role of CD6 has not been fully elucidated. However, it appears to play a role as both a costimulatorymolecule in T cell activation and as an adhesion receptor.CD6/ALCAM interactions have been postulated to play a role in thymocyte development. The CD6 intracellular domain contains regions that can interact with SH2 or SH3 containing proteins. However,the signaling pathways have not been elucidated.
Synonym: CD6 antigen, Cd6
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Molecular Weight
- 41.9 kDa
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UniProt
- Q91WN5
Target
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