Quick Overview for CD80 Protein (CD80) (His tag) (ABIN7320994)
Target
See all CD80 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This CD80 protein is labelled with His tag.
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Purpose
- Recombinant Rabbit B7-1/CD80 Protein (His Tag)
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Sequence
- Gly33-Gln241
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Characteristics
- Recombinant Rabbit CD80 is produced by our Mammalian expression system and the target gene encoding Gly33-Gln241 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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CD80 (CD80) (AA 35-242) protein (His-Avi Tag)
CD80 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD80 (CD80) (AA 35-242) protein (Fc Tag)CD80 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD80 (CD80) (AA 35-242) protein (His-Avi Tag,Biotin)CD80 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD80 (CD80) (AA 35-242) (Active) protein (Fc Tag)HPLC verified CD80 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD80 (CD80) (AA 35-242) protein (His tag)CD80 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD80 (CD80) (AA 35-242) protein (mFc-His Tag)CD80 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
CD80 (CD80) (AA 35-242) protein (His tag)HPLC verified CD80 Origin: Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
CD80 (CD80) (AA 38-246) protein (His tag)CD80 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD80 (CD80) (AA 137-230) protein (His-DYKDDDDK-Strep II Tag)CD80 Origin: Human Host: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
CD80 (CD80) (AA 35-242) protein (His-DYKDDDDK-Strep II Tag)CD80 Origin: Human Host: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD80
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Alternative Name
- B7-1/CD80
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Background
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Background: Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response.
Synonym: T-lymphocyte activation antigen CD80, Activation B7-1 antigen, B7, CD80
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Molecular Weight
- 24.5 kDa
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UniProt
- P42070
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Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Target
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