CD80 Protein (CD80) (mFc Tag)
Quick Overview for CD80 Protein (CD80) (mFc Tag) (ABIN7319714)
Target
See all CD80 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This CD80 protein is labelled with mFc Tag.
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Purpose
- Recombinant Human CD80/B7-1 Protein (mFc Tag)
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Sequence
- Val35-Leu242
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Characteristics
- Recombinant Human B7-1 Antigen is produced by our Mammalian expression system and the target gene encoding Val35-Leu242 is expressed with a mFc tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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CD80 (CD80) (AA 35-242) (Active) protein (His-Avi Tag)
CD80 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD80 (CD80) (AA 35-242) (Active) protein (Biotin,His-Avi Tag)CD80 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD80 (CD80) (AA 35-242) protein (His tag,mFc Tag)CD80 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM
CD80 (CD80) (AA 35-242) protein (His tag)HPLC verified CD80 Origin: Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
CD80 (CD80) (AA 137-230) protein (His-DYKDDDDK-Strep II Tag)CD80 Origin: Human Host: HEK-293T Cells Recombinant WB, ELISA, SDS, PI
CD80 (CD80) (AA 35-242) protein (His-DYKDDDDK-Strep II Tag)CD80 Origin: Human Host: HEK-293T Cells Recombinant WB, ELISA, SDS, PI
CD80 (CD80) (AA 38-245) (Active) protein (Fc Tag)CD80 Origin: Mouse Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD80 (CD80) (AA 35-242) (Active) protein (Fc Tag,AVI tag,Biotin)CD80 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
CD80 (CD80) protein (His tag)CD80 Origin: Rabbit Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
CD80 (CD80) protein (Fc Tag)CD80 Origin: Cynomolgus Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD80
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Alternative Name
- CD80/B7-1
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Background
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Background: Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4. Studies have shown that CTLA-4 binds mostly to CD80. The structure presents two extracellular domains: a membrane distal variable-like domain (IgV) and a membrane proximal Ig constant-like domain (IgC) along with an intracellular domain. Both IgV and IgC consist of anti-parallel beta sandwiches joined by a short linker region. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells.
Synonym: CD80, Activation B7-1 antigen, B7, BB1, CD28LG1, CD28LGB7-1 antigen, T-lymphocyte activation antigen CD80,B7-1,B7.1,CD28LG,LAB7
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Molecular Weight
- 50.5 kDa
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UniProt
- P33681
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Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Target
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