CD81 Protein (CD81)
Quick Overview for CD81 Protein (CD81) (ABIN7321051)
Target
See all CD81 ProteinsProtein Type
Origin
Source
Purity
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Purpose
- Recombinant Rat CD81/TAPA-1 Protein
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Sequence
- Lys116-Lys201
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Characteristics
- A DNA sequence encoding the rat Cd81 (NP_037219.1) (Lys116-Lys201) was expressed with two additional amino acids (Gly & Pro) at the N-terminus.
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Endotoxin Level
- < 1.0 EU per μg protein as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile PBS, pH 7.4
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD81
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Alternative Name
- CD81/TAPA-1
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Background
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Background: CD81, also known as TAPA-1, belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Members of this family mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.CD81 is a widely expressed cell-surface protein involved in an astonishing variety of biologic responses. It is related to adhesion, morphology, activation, proliferation, and differentiation of B, T, and other cells. On B cells CD81 is part of a complex with CD21, CD19, and Leu13. This complex reduces the threshold for B cell activation via the B cell receptor by bridging Ag specific recognition and CD21-mediated complement recognition.
Synonym: Tapa1
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Molecular Weight
- 9.7 kDa
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NCBI Accession
- NP_037219
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Pathways
- Inositol Metabolic Process, Hepatitis C
Target
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