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CD81 Protein (CD81) (AA 113-201) (hIgG-His-tag)

CD81 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN5854988
  • Target See all CD81 Proteins
    CD81
    Protein Type
    Recombinant
    Protein Characteristics
    AA 113-201
    Origin
    • 12
    • 2
    • 1
    Human
    Source
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Baculovirus infected Insect Cells
    Purification tag / Conjugate
    This CD81 protein is labelled with hIgG-His-tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    ADPFVNKDQI AKDVKQFYDQ ALQQAVVDDD ANNAKAVVKT FHETLDCCGS STLTALTTSV LKNNLCPSGS NIISNLFKED CHQKIDDLFS GKLEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H
    Purity
    > 95 % by SDS - PAGE
    Endotoxin Level
    < 1.0 EU per 1ug of protein (determined by LAL method)
    Top Product
    Discover our top product CD81 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    CD81
    Alternative Name
    CD81 (CD81 Products)
    Synonyms
    Tapa-1 Protein, Tapa1 Protein, Tspan28 Protein, CVID6 Protein, S5.7 Protein, TAPA1 Protein, TSPAN28 Protein, CD81 molecule Protein, CD81 molecule b Protein, CD81 antigen Protein, Cd81 molecule Protein, CD81 Protein, cd81b Protein, Cd81 Protein
    Background
    CD81, also known as CD81 antigen isoform 1, belongs to the tetraspanin family. It interacts directly with immunoglobulin superfamily member 8 (IGSF8, CD316) and CD36. In B cells, it is part of a complex with CD21, CD19 and Leu13. This complex reduces the threshold for B cell activation through B cell receptors by linking Ag specific recognition and CD21 mediator recognition. On T cells it associates with CD4 and CD8 and provides a costimulatory signal with CD3. Recombinant human CD81, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    Molecular Weight
    37.0kDa (331aa) 40-57kDa (SDS-PAGE under reducing conditions)
    NCBI Accession
    NP_004347
    UniProt
    P60033
    Pathways
    Inositol Metabolic Process, Hepatitis C
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