Quick Overview for CD82 Protein (CD82) (Fc Tag) (ABIN7319825)
Target
See all CD82 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This CD82 protein is labelled with Fc Tag.
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Purpose
- Recombinant Human CD82 (N-Fc)
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Sequence
- Gly103-Gln225
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Characteristics
- Recombinant Human CD82 Antigen is produced by our Mammalian expression system and the target gene encoding Gly103-Gln225 is expressed with a Fc tag at the N-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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CD82 (CD82) (AA 1-266) protein (His tag)
custom-made CD82 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
CD82 (CD82) (AA 1-267) protein (His tag)custom-made CD82 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
CD82 (CD82) (AA 1-267) protein (GST tag)CD82 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
CD82 (CD82) (AA 111-227), (Extracellular) protein (His-SUMO Tag)CD82 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD82
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Alternative Name
- CD82
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Background
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Background: CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1 suppresses EMT in prostate cancer cells adhered to fibronectin leading to reduced cell migration and invasiveness. CD82/Kai-1 function is important for muscle stem cell function in muscular disorders. Overexpression of CD82/Kai-1 suppresses growth, migration and invasion of oral cancer cells and may be considered as a potential therapeutic target in oral cancer.
Synonym: CD82 antigenC33, CD82 Molecule, CD82, IA4, IA4C33 antigen, Inducible membrane protein R2, KAI1, KAI1GR15, ST6, ST6tspan-27, Suppressor of tumorigenicity 6 protein, Tetraspanin-27, TSPAN27, Tspan-27, TSPAN274F9
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Molecular Weight
- 40.3 kDa
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UniProt
- P27701
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Pathways
- p53 Signaling
Target
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