CD96 Protein (CD96) (His tag)

Catalog No. ABIN7319442

This Recombinant CD96 protein is expressed in Human Cells.

Quick Overview for CD96 Protein (CD96) (His tag) (ABIN7319442)

Target: CD96

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Human Cells

Purity: > 90 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This CD96 protein is labelled with His tag.

Purpose: Recombinant Human CD96 Protein (His Tag)(Active)

Sequence: Val22-Met503

Characteristics: Recombinant Human CD96 is produced by our Mammalian expression system and the target gene encoding Val22-Met503 is expressed with a 6His tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Immobilized Human PVR-His(Cat: PKSH033563) at 10μg/ml(100 μl/well) can bind Biotinylated Human CD96-His. The ED50 of Human CD96-His is 27.54μg/mL.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: CD96

Alternative Name: CD96

Background:

Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. The CD155 ligand CD96 is a member of the Ig superfamily. It's a immunoglobulin-like protein tentatively allocated to the repertoire of human NK receptors. NK cells recognize poliovirus receptor (PVR), anectins and nectin-like protein family member serve to mediate cell-cell adhesion, cell migration, with the presence of an additional receptor, CD96. CD96 promotes NK cell adhesion to target cells expressing PVR, stimulates cytotoxicity of activated NK cells, and mediates acquisition of PVR from target cells.

Synonym: T-cell surface protein tactile, Cell surface antigen CD96, T cell-activated increased late expression protein, CD96

Molecular Weight: 54.4 kDa