Quick Overview for CD99 Protein (CD99) (His tag) (ABIN7319789)
Target
See all CD99 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This CD99 protein is labelled with His tag.
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Purpose
- Recombinant Human CD99/MIC2 (C-6His)
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Sequence
- Asp23-Asp122
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Characteristics
- Recombinant Human CD99 is produced by our Mammalian expression system and the target gene encoding Asp23-Asp122 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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CD99 (CD99) (AA 25-122) protein (His-IF2DI Tag)
CD99 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
CD99 (CD99) (AA 23-122) protein (Fc Tag)CD99 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
CD99 (CD99) (AA 1-185) protein (GST tag)CD99 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
CD99 (CD99) (AA 23-122) protein (hIgG-His-tag)CD99 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95% by SDS-PAGE SDS
CD99 (CD99) protein (Fc Tag)CD99 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
CD99 (CD99) protein (Fc Tag)CD99 Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD99
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Alternative Name
- CD99/MIC2
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Target Type
- Viral Protein
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Background
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Background: CD99 is a type I transmembrane glycoprotein and the founding member of the CD99 family of molecules. The extracellular domain of CD99 contains no identifiable motifs, its cytoplasmic region, although short, does have signal transduction capability. Cells known to express CD99 include fibroblasts, neutrophils, T cells, double positive thymocytes, CD34+ stem cells, monocytes and endothelial cells. Two types of CD99 isoforms have been classified. Native human CD99 is referred to as the long, or type I isoform. The best studied type II isoform shows an Asp-Gly substitution for the C terminal 27 amino acids. The type I and II isoforms have distinctive signal transduction pathways (FAKsrc for type I PI3K plus srcERK1/2 for type II), and mediate clearly different biological outcomes. Homophilic interaction between CD99 on the neutrophil and CD99 on the endothelial cell regulates the transendothelial migration of neutrophils during inflammation. Human CD99 has 48 % aa sequence identity to mouse CD99.
Synonym: CD99 Antigen, 12E7, E2 Antigen, Protein MIC2, T-Cell Surface Glycoprotein E2, CD99, MIC2, MIC2X, MIC2Y
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Molecular Weight
- 11.13 kDa
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UniProt
- P14209
Target
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