Claudin 11 Protein (CLDN11) (Fc Tag)
Quick Overview for Claudin 11 Protein (CLDN11) (Fc Tag) (ABIN7317330)
Target
See all Claudin 11 (CLDN11) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This Claudin 11 protein is labelled with Fc Tag.
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Purpose
- Recombinant Human CLDN11/Claudin-11 Protein (Fc Tag)
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Sequence
- Val23-Arg82
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Characteristics
- A DNA sequence encoding the human CLDN11 (O75508) (Val23-Arg82) was expressed with the Fc region of mouse IgG1 at the N-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Claudin 11 (CLDN11) (AA 1-207) protein (His tag)
custom-made CLDN11 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Claudin 11 (CLDN11) (AA 1-207) protein (His tag)custom-made CLDN11 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Claudin 11 (CLDN11) (AA 1-207) protein (GST tag)CLDN11 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile PBS, pH 7.4
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Claudin 11 (CLDN11)
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Alternative Name
- CLDN11/Claudin-11
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Background
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Background: Claudin-11, also known as CLDN11, belongs to the group of claudins. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands function as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions.Claudin-11 is a tight junction associated protein and is a major component of central nervous system (CNS) myelin that is necessary for normal CNS function. Human blood-testis barrier disruption is related to a dysfunction of CLDN11 gene. It plays an important role in regulating proliferation and migration of oligodendrocytes.
Synonym: OSP,OTM
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Molecular Weight
- 33.2 kDa
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UniProt
- O75508
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Pathways
- Hepatitis C
Target
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