Clusterin Protein (CLU) (His tag,Fc Tag)
Quick Overview for Clusterin Protein (CLU) (His tag,Fc Tag) (ABIN7318318)
Target
See all Clusterin (CLU) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This Clusterin protein is labelled with His tag,Fc Tag.
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Purpose
- Recombinant Human Clusterin/ApoJ Protein (Fc & His Tag)
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Sequence
- Asp23-Glu449
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Characteristics
- Recombinant Human Clusterin is produced by our Mammalian expression system and the target gene encoding Asp23-Glu449 is expressed with a Fc, 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Clusterin (CLU) (AA 22-448) protein (His tag)
CLU Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Clusterin (CLU) (AA 23-449) protein (His tag)CLU Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Clusterin (CLU) (AA 184-293) protein (His-IF2DI Tag)CLU Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Clusterin (CLU) (AA 402-501) protein (GST tag)CLU Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Clusterin (CLU)
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Alternative Name
- Clusterin/ApoJ
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Background
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Background: Clusterin is a secreted protein which belongs to the Clusterin family. Clusterin is expressed in adult testis, heart, ovary, adrenal gland, brain and liver. Clusterin has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. In addition,Clusterin is up/ down regulated on the mRNA or protein level in many pathological and clinically relevant situations including cancer, organ regeneration, infection, Alzheimer disease, retinitis pigmentosa, myocardial infarction, renal tubular damage, autoimmunity and others.
Synonym: Clusterin, Aging-Associated Gene 4 Protein, Apolipoprotein J, Apo-J, Complement Cytolysis Inhibitor, CLI, Complement-Associated Protein SP-40, Ku70-Binding Protein 1, NA1/NA2, Testosterone-Repressed Prostate Message 2, TRPM-2, CLU, APOJ, CLI, KUB1,AAG4,APO-J,CLU1,CLU2,NA1/NA2,SGP-2,SGP2,SP-40
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Molecular Weight
- 78.0 kDa
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UniProt
- P10909
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Pathways
- Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
Target
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